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Medical Coding Guide — Updated 2026

CC vs MCC in ICD-10 — What's the Difference?

A complete guide to CC and MCC codes in ICD-10-CM. Learn how Complications and Comorbidities vs Major Complications affect MS-DRG assignment and hospital reimbursement.

📅 Updated April 2026 ⏱ 8 min read 🏢 CMS FY2026
CC/MCC CodingHospital CodingMS-DRGReimbursementCMS FY2026

Table of Contents

  1. What Are CC and MCC Codes?
  2. How CC and MCC Codes Affect MS-DRG Assignment
  3. Examples of CC and MCC Codes
  4. The Role of the Principal Diagnosis
  5. When to Query the Physician
  6. CC/MCC Changes for FY2026
  7. CC vs MCC — Quick Reference

What Are CC and MCC Codes?

In ICD-10-CM coding, CC stands for Complication or Comorbidity and MCC stands for Major Complication or Comorbidity. These designations are assigned by CMS to specific diagnosis codes based on their clinical severity and the additional resources they require during a hospital stay.

CC and MCC codes are critical to hospital reimbursement because they directly affect the MS-DRG (Medicare Severity Diagnosis Related Group) assignment — and therefore the amount Medicare pays the hospital for that patient encounter.

Simple rule: MCCs represent the most severe conditions. CCs are significant but less severe. Both increase reimbursement — MCCs more so than CCs.

How CC and MCC Codes Affect MS-DRG Assignment

Most MS-DRGs have three payment levels based on the presence of CCs and MCCs in the claim:

MS-DRG Hierarchy Example — Pneumonia

MS-DRGDescriptionPayment Level
193Pneumonia with MCCHighest
194Pneumonia with CCMiddle
195Pneumonia without CC/MCCLowest

When a patient is admitted with pneumonia and also has acute respiratory failure (an MCC), the hospital bills under DRG 193 and receives significantly higher reimbursement than if no CC or MCC was present. The difference can be thousands of dollars per case.

Examples of CC and MCC Codes

Not all diagnoses qualify as CC or MCC codes. CMS publishes the official CC/MCC list annually as part of the IPPS Final Rule. Here are common examples:

Common MCC Codes (Most Severe)

ICD-10 CodeDescriptionDesignation
J96.00Acute respiratory failure, unspecifiedMCC
E11.10Type 2 diabetes with ketoacidosisMCC
A41.9Sepsis, unspecified organismMCC
I50.9Heart failure, unspecifiedCC
N18.4Chronic kidney disease, stage 4CC
E11.65Type 2 diabetes with hyperglycemiaCC

The Role of the Principal Diagnosis

An important rule: a CC or MCC only counts toward DRG assignment if it is a secondary diagnosis. The principal diagnosis — the condition primarily responsible for the admission — cannot be its own CC or MCC. It must be a comorbidity or complication that coexists with the principal diagnosis.

Additionally, not all secondary diagnoses qualify as CCs or MCCs in every case. CMS maintains an exclusion list that prevents certain diagnoses from functioning as CCs or MCCs when paired with specific principal diagnoses, to prevent inappropriate upcoding.

Documentation matters: A CC or MCC code can only be assigned when the physician has clearly documented the condition in the medical record and it meets the UHDDS definition of a reportable diagnosis — meaning it was evaluated, treated, or affected the patient's care during the stay.

When to Query the Physician

Coders often identify clinical indicators in the record that suggest a CC or MCC condition may be present but has not been explicitly documented. In these situations, a clinical documentation integrity (CDI) query is appropriate. Common query opportunities include:

Querying is not upcoding — it is ensuring the coded record accurately reflects the severity of the patient's condition.

CC/MCC Changes for FY2026

CMS updates the CC and MCC designation list annually with each IPPS Final Rule. For FY2026 (effective October 1, 2025), coders should verify current designations using updated references rather than prior year lists, as codes can be added, removed, or reclassified between MCC and CC.

ICD10Source uses the official CMS FY2026 IPPS Final Rule CC/MCC data and flags all 1,404 CC and MCC codes directly in search results.

CC vs MCC — Quick Reference

FeatureCCMCC
Severity levelSignificantMost severe
Reimbursement impactModerate increaseLargest increase
DRG tierMiddle tierTop tier
FY2026 code count1,071 codes333 codes
Must beSecondary diagnosisSecondary diagnosis
Documentation requiredYes — clinically evaluatedYes — clinically evaluated

📄 Official Sources & References

The information in this guide is based on official U.S. government publications. Always verify coding information against the most current official sources before use in billing or clinical documentation.

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